Home > Offer to Sell > Intermediates > Pharmaceutical_intermediates > Acitretin

Acitretin

Inquiry

Post Date:	Apr 05,2025
Expiry Date:	Oct 02,2025
Detailed Description:	Cas No. :55079-83-9 Acitretin Product Name: Acitretin SPEC:EP6.0 CAS No.:55079-83-9 MFC21H26O3 Melting Point: 228-230°C Packing: 25kg/drum Appearance: Yellow crystalline powder Storage: Sealed tightly and stored away from light in a cool and dry place. Place of origin: China. Validity: 2 years Packing: 1kg/foil bag, or 25kg/carton drum Product Description: Acitretin (trade names Soriatane and Neotigason) is a second-generation retinoid. It is taken orally, and is typically used forpsoriasis. It is a metabolite of etretinate, which was used prior to the introduction of acitretin. Etretinate was discontinued because it had a narrow therapeutic index as well as a long elimination half-life(t1/2=120 days), making dosing difficult. In contrast, acitretin's half-life is approximately 2 days. However, because acitretin can be reverse metabolised into etretinate which has an extremely long half-life, women must avoid becoming pregnant for at least 3 years after discontinuing acitretin. Therefore, acitretin is generally not recommended for women of child-bearing age with a risk of becoming pregnant. Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis. Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments. It binds to nuclear receptors that regulates gene transcription. They induce keratinocytedifferentiation and reduce epidermal hyperplasia, leading to the slowing of cell reproduction. Acitretin is readily absorbed and widely distributed after oral administration. A therapeutic effect occurs after 2 to 4 weeks or longer. Patients that have received the medication are advised against giving blood for at least 3 years due to the risk of birth defects. Applications: Acitretin (CAS NO.55079-83-9) is a synthetic retinoid which is the major metabolite of etretinate. It is typically used for psoriasis. Acitretin is a metabolite of etretinate, which was used prior to the introduction of acitretin. Specification Test Items Standard Result Description A yellow or greenish-yellow crystalline powder conform Identification Shall comply All comply Loss on dressing ≤0.5% 0.32% Sulphated ash ≤0.1 0.09% Heavy metals ≤20ppm conform Related substance Individual impurities ≤0.3 0.21% Total impurities ≤1.0% 0.40% Assay(on dried basis) 98.0%-102.0% 99.5% Conclusion The results conform with EP6.0 Competitive Advantages Well and High Quality Control , Prompt Delivery , Competitive Prices , Earth-friendly Products , Small Order Acceptable

CAS Registry Number:	55079-83-9
Synonyms:	;9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid;Neotigason;Soriatane;acitretin;(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid;(2Z,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid;
Molecular Formula:	C₂₁H₂₆O₃
Molecular Weight:	326.4293
Molecular Structure:
Hazard Symbols:	T:Toxic; N:Dangerous for the environment;
Risk Codes:	R36/38:; R61:; R50/53:;
Safety Description:	S53:; S37/39:; S45:; S60:; S61:;

Company:	Taizhou Tianrui Chempharm Co., Ltd. [ China ]
Contact:
Tel:	+86-576-88603301
Fax:	+86-576-88603302
Email:	sales@tianruipharm.com

Disclaimer statement:The information and data included above have been realized by the enterprises and compiled by the staff, and are subject to change without notice to you. The Chemnet makes no warranties or representations whatsoever regarding the facticity, accuracy and validity of such information and data. In order to ensure your interest, we suggest you chose the products posted by our gold suppliers or VIP members.

潘金莲被吸乳揉到高潮的视频,久久99久久99精品免观看,在电影院里拨开内裤挺进,护士交换粗吟配乱大交动态图

Acitretin

Inquiry

55079-83-9