L-Glutamate Decarboxylase (Crude Enzyme)
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Post Date:
May 21,2024
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Expiry Date:
Nov 17,2024
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Detailed Description:
Cas No. :9024-58-2
Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO 2. In mammals, GAD exists in two isoforms encoded by two different genes - GAD1 and GAD2. These isoforms are GAD67 and GAD65 with molecular weights of 67 and 65 kDa, respectively. GAD1 and GAD2 are expressed in the brain where GABA is used as a neurotransmitter, GAD2 is also expressed in the pancreas. At least two more forms, GAD25 and GAD44 (embryonic; EGAD) are described in the developing brain. They are coded by the alternative transcripts of GAD1, I-80 and I-86: GAD25 is coded by both, GAD44 - only by I-80.This product with the indicated enzyme activity was briefly purified from engineered E. coli. https://www.creative-enzymes.com/product/LGlutamate-Decarboxylase-Crude-Enzyme-_16244.html
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CAS Registry Number:
9024-58-2
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